Biohacking Report 2026: 494 remedies in the fact check

The numbers at a glance

How good is the evidence?

Each remedy gets a label that follows from human evidence, direction of the data and hype gap according to fixed rules. This is how the 494 entries are distributed:

The largest group is “supported, with caveats” (141), closely followed by “thin human evidence” (132): there are studies in humans, but they are too small, too short or have mixed results.

What really holds up is often unspectacular

The 31 well-supported entries are almost exclusively basics and approved medicines: Creatine monohydrate, Omega-3 (EPA/DHA), Caffeine, Whey protein, Semaglutide (Ozempic / Wegovy), Tirzepatide (Mounjaro / Zepbound), Tadalafil, Viagra (Sildenafil), Cutting down on alcohol, No caffeine after 2 p.m., 10 min of sunlight in the morning, Midday sun for vitamin D, Strength training 3× per week, HIIT 1–2× per week, Optimizing iron levels & hemoglobin, Nandrolone decanoate, Potassium, Abaloparatide, Teriparatide, Vitamin A (retinol), Liraglutide (Saxenda / Victoza), Bempedoic acid (Nilemdo), Orlistat (Xenical / alli), Vardenafil (Levitra), Avanafil (Spedra), Ecnoglutide, Statins (atorvastatin, rosuvastatin), Colchicine (low-dose, cardiovascular prevention), Orexin receptor antagonists (daridorexant, suvorexant, lemborexant), Dapoxetine (Priligy), Alprostadil (Caverject, MUSE, Vitaros).

Not a single one of the research peptides on the market makes it into this group.

Real active substances, exaggerated promises

The problem is not only fantasy products. For 38 remedies, the effect is well supported, but the advertising promises considerably more than the studies show. Examples: Vitamin D3, Metformin, Testosterone & TRT, HGH (growth hormone / somatropin), Retatrutide, Orforglipron (Foundayo), Ginkgo biloba, NAC (N-acetylcysteine), Minoxidil, Finasteride.

The peptide gap

Among peptides and experimental substances, 70 of 215 entries (33%) are either never studied in humans or heavily overhyped. Among supplements it is 10 of 159 (6%), among the Russian bioregulators 13 of 14.

Never studied in humans are, for example, TB-500 (Thymosin Beta-4 Fragment), Epitalon (Epithalon), 5-Amino-1MQ, SLU-PP-332, MOTS-c, Humanin, FOXO4-DRI, KPV, Stenabolic (SR9009), YK-11. The advertising runs far ahead of the evidence with, for example, CJC-1295 + Ipamorelin, GLP-3, RAD140 (Testolone), Semax, Melanotan 2, NAD+ infusion, Exosome therapy, Therapeutic plasma exchange (TPE), Klotho.

Studied and not confirmed

22 remedies and practices were properly studied without the advertised benefit being confirmed: Aspirin for prevention (primary prevention), Nicotine without smoke (pouches, patches, lozenges), Cancer blood test (multi-cancer early detection), Micronutrient concentrates (LaVita & Co.), Resveratrol, Glucosamine, Serrapeptase, AOD-9604, Cerebrolysin, Dasatinib + Quercetin (senolytic stack), Larazotide (AT-1001), Chelation therapy, PRP (platelet-rich plasma), CGM – continuous glucose monitoring, Dual N-Back for working memory, Lipoprotein(a), Clenbuterol, Liothyronine (T3), Neurofeedback (EEG biofeedback), LSD microdosing, Evening primrose oil, Ivermectin.

Long used, barely tested

For 21 entries, there is a lot of experience of use, but hardly any studies: Lion's Mane, Chaga (Inonotus obliquus), SNAP-8 (Acetyl Octapeptide-3), IV vitamin therapy (Myers' cocktail), Cutting carbohydrates in the evening, Filtered water with minerals, No phone in the first hour, Measuring glucose continuously (CGM), Aligning training with the cycle (women), 24–72 h extended fasting, Fasting for women – cycle-adjusted, Coffee as a fasting booster, Metenolone (Primobolan), Drostanolone (Masteron), Oral-Turinabol (dehydrochlormethyltestosterone), Pau d’Arco (Lapacho), Manganese, Molybdenum, Dandelion root, Ketoconazole shampoo, Phenylpiracetam.

How the BK-Score is made

Each remedy is rated on five axes from 0 to 10: human evidence, mechanism, safety data, hype gap and track record of use. The basis is primary sources: meta-analyses, randomized trials, approval documents and information from authorities. The score rates how well a remedy has been studied, not whether it is good or bad, and it is not a recommendation. The full method is described in the Methodology, and each rating is justified with sources on the respective topic page.

Data and download

Table of all 494 entries (CSV)Report as PDF

Numbers, charts and table may be used freely with attribution (CC BY 4.0 license).

How to cite the report: Biohacking Kompakt (2026): Biohacking Report 2026 – 494 remedies in the fact check. https://biohackingkompakt.de/en/report/2026.html

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